Figure 1: Exposure to the UCS but not the CS memory retrieval-extinction manipulation decreased renewal and cocaine-priming-induced reinstatement when nose-poke responding during testing was reinforced by a non-extinguished discrete CS. | Nature Communications

Figure 1: Exposure to the UCS but not the CS memory retrieval-extinction manipulation decreased renewal and cocaine-priming-induced reinstatement when nose-poke responding during testing was reinforced by a non-extinguished discrete CS.

From: A novel UCS memory retrieval-extinction procedure to inhibit relapse to drug seeking

Figure 1

(a) Timeline of the experimental procedure. (b,c) The mean number of responses on the active and inactive nose-poke devices during the extinction phase and reinstatement tests.*Different from ‘saline +1 h+extinction’, mixed ANOVA, *P<0.05; n=7–8 per experimental condition. Error bars represent s.e.m. See Methods and Results for details of the experimental procedure.

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