Figure 8: Exposure to methylphenidate 1 h before extinction training accelerated extinction responding and decreased spontaneous recovery of cocaine seeking.
From: A novel UCS memory retrieval-extinction procedure to inhibit relapse to drug seeking
(a) Timeline of the experimental procedure. (b,c) The mean number of responses on the active and inactive nose-poke devices during the extinction phase and spontaneous recovery test. *Different from ‘saline+1 h+extinction’, mixed ANOVA, *P<0.05; n=9 per experimental condition. Error bars represent s.e.m. MPH, methylphenidate.
