Table 1 The characteristics of study subjects.

From: Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels

 

GWAS

Replication 1

Replication 2

Number

3,294

4,023

2,042

Sex (female ratio) (%)

66.5

67.0

68.8

Age* (year)

52.3±14.1

55.3±12.6

53.1±12.9

AAT* (mg dl−1)

133.0±19.4

128.5±17.6

135.4±19.0

BMI* (kg m−2)

22.3±3.2

22.3±3.3

22.3±3.3

Brinkman index*

164.6±319.8

167.2±325.5

149.4±307.6

Alcohol intake† (heavy/moderate/mild)

713/377/2,204

959/379/2,685

466/199/1,377

High-sensitive CRP* (ng ml−1)

922.1±3261

937.6±4108

786.5±2548

  1. AAT, Alpha-1 antitrypsin; BMI, body mass index; CRP, C-reactive protein; GWAS, genome-wide association studies.
  2. *The mean±s.d.
  3. †Heavy: >3 days week−1, moderate: 2–3 days week−1, mild <2 days week−1.
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