Figure 5: Structures of covalently modified Ypt7. | Nature Communications

Figure 5: Structures of covalently modified Ypt7.

From: Locking GTPases covalently in their functional states

Figure 5

Detailed views and comparison of the nucleotide-binding regions of the previously published Ypt7:GppNHp (a) with covalently modified Ypt7–aGppNHp (chain A) (b) and Ypt7–aGTP (c) as well as the previously published Ypt7:GDP (d) and the covalently modified Ypt7–aGDP (e). The switch I and II regions are shown in red and blue, respectively, the 2Fo−Fc electron density (black mesh) around the modified Cys, the linker and the nucleotide is depicted at 1σ.

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