Figure 6: Neomycin and paromomycin rinse off of h44 but not H69. | Nature Communications

Figure 6: Neomycin and paromomycin rinse off of h44 but not H69.

From: Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions

Figure 6

Aminoglycoside real-time deliveries and rinse-outs were performed on wild-type ribosomes. For both (a) neomycin and (b) paromomycin, five population FRET histograms are shown representing the chronological order of the experiment. Left to right: (1) no drug; (2) real-time delivery of 10 μM aminoglycoside; (3) aminoglycoside equilibrium; (4) real-time rinse-out; (5) 90 s following rinse-out.

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