Table 2 Clinical characteristics of CP probands.

From: Clinically relevant copy number variations detected in cerebral palsy

Patient characteristics

N=147

 Age in years (range)

7.86±3.15 (4–16)

 Gender

Male

81 (55%)

Female

66 (45%)

Phenotypic characteristics

 CP Subtype

Spastic hemiplegia

55 (37.4%)

Spastic diplegia

34 (23.1%)

Spastic triplegia

6 (4.1%)

Spastic quadriplegia

31 (21.1%)

Ataxic CP

4 (2.7%)

Dyskinetic CP

12 (8.2%)

Unknown

5 (3.4%)

 GMFCS

I

59 (40.1%)

II

28 (19.0%)

III

13 (8.8%)

IV

19 (12.9%)

V

15 (10.2%)

Unknown

13 (8.8%)

 Cortical visual impairment*

17.8%

 Sensorineural auditory impairment†

10.9%

 Communication difficulties‡

70.9%

 Cognitive impairment§

42.5%

 Feeding difficulties||

11.1%

 Neonatal seizures

18.3%

 Epilepsy#

15.5%

  1. CP, Cerebral palsy; GMFCS, Gross Motor Function Classification System
  2. *Cortical visual impairment status was available for 126 individuals.
  3. †Sensorineural auditory impairment status was available for 128 individuals.
  4. ‡Status regarding communication difficulties was available for 134 individuals.
  5. §The presence of cognitive impairment could be examined in 87 individuals.
  6. ||Gavage feeding and/or feeding by gastrostomy could be determined in 144 subjects.
  7. We could evaluate the presence or absence of convulsions within the first 72 h for 120 individuals.
  8. #The presence or absence of seizures in the last 12 months could be determined in 142 subjects.
Back to article page