Figure 2: Allelic frequency relationships between old and modern populations for 150,647 SNPs.
From: Museum samples reveal rapid evolution by wild honey bees exposed to a novel parasite
Allele frequencies were subjected to angular transformation to stabilize variance, following Fisher and Ford65. The markers highlighted in red show significant differences between old and modern populations according to both a test based on allele frequencies and a test based on haplotype frequencies. When divided by the s.d., neutral changes in allele frequencies should follow the standard normal distribution (blue line). The 95% confidence interval for possible allele frequency shifts resulting from the joint action of drift and immigration is shown in grey. We used the interquartile range (IQR/1.349) as a robust estimate of the s.d. Allele frequencies should be correlated within a population sampled at various times, scattered around the line y=x (blue). Points have been rendered transparent to minimize over-plotting. Left over from previous figure version. However, most of the loci are consistent with population genetic expectations for neutrally fluctuating variants.
