Figure 7: Biological importance of the verapamil-binding site in NorM-NG.
From: Structural basis for the blockade of MATE multidrug efflux pumps
The inhibition of bacterial growth as measured by attenuance at 600 nm. Bacteria expressing the NorM-NG variants or pET-15b were grown in the presence of 150 μM verapamil (cyan column, a); or in the presence of 0.5 μg ml−1 ethidium, with (cyan column) or without (red column) 50 μM verapamil (b). Error bars indicate s.d. among three biological replicates.
