Figure 5: Profiling gene expression in HDAC4*-electroporated rd1 retinas at P12 by quantitative PCR. | Nature Communications

Figure 5: Profiling gene expression in HDAC4*-electroporated rd1 retinas at P12 by quantitative PCR.

From: A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa

Figure 5

(a) The mRNA levels of photoreceptor genes in HDAC4*-electroporated rd1 retinas relative to the GFP-electroporated rd1 retinas. (b) Assay of gene expression for transcriptional factors and cell cycle genes. (c) Assay of gene expression for endoplasmic reticulum stress and oxidative stress genes. (d) Assay of gene expression for cell death/apoptosis genes. Dashed lines in b–d indicate mRNA levels in the wild-type retina. *P<0.05, **P<0.01, ***P<0.001. Data are presented as mean±s.d., n=3.

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