Figure 4: Continuous photobleaching results
From: Loss of lamin A function increases chromatin dynamics in the nuclear interior
(a) Normalized CP curves of free eGFP protein (blue) and GFP–pre-lamin A in MF cells (red). The intersection of the linear long-time fit (dashed black) and y-axis provides the free fraction (59% in the presented curve). (b) Histogram of the values of free fraction of eGFP–pre-lamin A in MF cells (27 repeats). The average free fraction is 63±12%.
