Table 1 Susceptibility of the human promyelocytic cell line HL60 (undifferentiated and differentiated) and primary human neutrophils to LukSF-PV, LukED and their hybrid leukotoxins.
From: Counter inhibition between leukotoxins attenuates Staphylococcus aureus virulence
| Â | Standard toxins | Hybrid toxins | ||
|---|---|---|---|---|
Cells | LukSF-PV | LukED | LukS-PV+ LukD | LukE+ LukF-PV |
Undifferentiated HL60 cells | −* | +†| − | + |
Macrophage-like HL60 cells | +++‡ | − | ++§ | − |
PMN-like HL60 cells | ++++|| | − | − | − |
Primary human neutrophils | ++++ | +++ | +++ | +++ |
