Figure 3: Prediction of ECSs.

(a) Overview of approaches to predicting proximal ECSs (Approach 1) and distal, intronic ECSs (Approach 2). (b) Numbers of editing sites identified in predicted ECSs (blue) compared with the control regions (red) of the same length indicated in (a). (c) The distribution of the distances between the editing site and the corresponding base in the ECS. (d,e) The distribution of (d) stem lengths and (e) max bulge sizes in the editing site side of the stem. The colour legend is the same as in (c). (f) The fraction of editing substrates that are base-paired at each position relative to the editing site (position 0, indicated in red), based on the predicted editing substrate structure. Negative positions are upstream (5′) of the editing site; positive positions are downstream (3′).