Figure 4: Conformational changes of P[11] HRV VP8* upon binding to glycans.
From: Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus
(a) Structural comparison of the P[11] HRV apo structure (light blue) with the liganded P[11] HRV VP8* (grey) with LNnT (type II), with the inlet showing the close-up view of the structural changes in a different orientation. (b) Structural comparison of the P[11] HRV apo structure (light blue) with the liganded P[11] HRV VP8* (grey) with LNT (type I), with the inlet showing the close-up view of the structural changes as in a. The interacting residues are shown in stick model, and the glycan residues are labelled as in Fig. 3. Changes in the sidechain orientations are indicated by black arrows.
