Table 1 Neutralization IC50 titres (μg ml−1) for the indicated immunomodulatory bispecific and control proteins against three representative HIV-1 strains from clades A, B and C.
From: Activation and lysis of human CD4 cells latently infected with HIV-1
Virus | Clade | VRC07 IgG | VRC07 Fab | VRC07-αCD3 |
|---|---|---|---|---|
Q23.17.SG3 | A | 0.036 | 0.056 | 0.025 |
AC10.29.SG3 | B | 0.114 | 0.576 | 0.346 |
ZM53.12.SG3 | C | 0.217 | 0.524 | 0.240 |
