Figure 3: Scope of anilines.
Reaction conditions: anilines 1a–j (0.25 mmol), methyl propiolate 2a (0.275 mmol), [Rh(cod)Cl]2 (2.5 mol%), dppm (10 mol%), (HCHO)n (2.5 equiv.) and 250 μl of H2O were heated at 100 °C under closed viol for specified time and depicted yields are isolated yields (yields in parentheses are recovery of the starting material). *Yield based on 1H NMR of crude reaction mixture using toluene as an internal standard (using 1 mol% of the rhodium catalyst).
