Figure 4: Scope of alkynes. | Nature Communications

Figure 4: Scope of alkynes.

From: Reversed reactivity of anilines with alkynes in the rhodium-catalysed C–H activation/carbonylation tandem

Figure 4

Reaction conditions: 0.25 mmol of 3,4-(methylenedioxy)aniline (1a) or 3,4-domethoxyaniline (1m), alkynes (0.275 mmol), [Rh(cod)Cl]2 (2.5 mol%), dppm (10 mol%), (HCHO)n (2.5 equiv.) and 250 μl of H2O were heated at 100 °C under closed viol for specified time and depicted yields are isolated yields (yields in parentheses are recovery of the starting material).

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