Figure 7: Rhodium-catalysed carbonannulation of ortho-vinylanilines using CO (surrogate) in water. | Nature Communications

Figure 7: Rhodium-catalysed carbonannulation of ortho-vinylanilines using CO (surrogate) in water.

From: Reversed reactivity of anilines with alkynes in the rhodium-catalysed C–H activation/carbonylation tandem

Figure 7

Reaction conditions: ortho-vinylanilines 5a–g (0.25 mmol), [Rh(cod)Cl]2 (2.5 mol%), dppm. (10 mol%), (HCHO)n (3 equiv.) and 250 μl of H2O were heated at 100 °C under closed viol for specified time and the yields in parenthesis are recovery of unreacted starting material. *Yields based on 1H NMR of the reaction mixture (using 1 mol% of the rhodium catalyst).

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