Figure 8: Mechanistic investigation. | Nature Communications

Figure 8: Mechanistic investigation.

From: Reversed reactivity of anilines with alkynes in the rhodium-catalysed C–H activation/carbonylation tandem

Figure 8

(a) Irreversibility of regioselective C–H bond activation of 1a. (b) Isolation of intermediates (C–C cross-coupled product) followed by carbonylation reaction. (c) Reaction of 1c with methyl propiolate (2a) in the absence of CO source. (d) Rhodium-catalysed auto-tandem reaction with labelled compounds. (e) Rhodium-catalysed CO formation from paraformaldehyde. (f) Kinetic isotopic experiments. (Yields in parentheses are isolated yields).

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