Table 1 Clinical parameters of EAE after adoptive transfer of old CD4+ T cells.

From: Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2

Experimental group

Disease incidence

Disease onset (mean±s.e.m.)

Maximum score (mean±s.e.m.)

WT T-cell transfer

6/11 (54.5%)

29.0±3.8

1.41±0.49

KO T-cell transfer

10/11 (90.9%)

20.0±2.6

2.95±0.44*

  1. Data are pooled from two independent experiments, each with 5 or 6 mice per experimental cohort (total 11 mice per group). *P<0.05 (Mann–Whitney test).
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