Figure 8: Correlation of POH1 expression with E2F1 target gene signature in HCC dataset.
From: POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation
(a) Transcript levels of POH1, Survivin and FOXM1 in non-tumoral liver and HCC tissues from the GSE14520 data set. The expression levels of these genes were compared using t-test. (b) The expression of POH1 correlates with Survivin and FOXM1 levels. The Pearson correlation analyses were performed. (c) Gene set enrichment analysis of the HCC dataset GSE14520 based on a signature of E2F1 target genes and POH1 expression.
