Table 2 The effect of AG1 and gatastatin on GTP-binding activity of γ-tubulin in vitro.

From: The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle

Compound

Concentration (μM)

GTP binding (control %)

AG1

60

93.7±11.7

Gatastatin

60

6.7±3.7

  1. GTP-binding inhibition (control %) by compounds was calculated as described in Methods section. Values are the mean±s.d.