Table 1 The Kd (DNA) values of WT and mutant HsPOLγ holoenzymes (HsPOLγA/HsPOLγB in complex).

From: Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies

Polγ holoenzyme

DNA binding Kd (nM)

WT

5.5±1.4

D274A

2.8±0.1

Q1102A

3.8±0.2

H1134A

3.5±0.5

  1. WT, wild type.
  2. Table shows values of dissociation constants as an average from three independent binding assays with errors presented as s.d.
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