Figure 2: Crystal structural of the globular head complexed with Fab of three representative mAbs. | Nature Communications

Figure 2: Crystal structural of the globular head complexed with Fab of three representative mAbs.

From: Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection

Figure 2

(a) The crystal structure of the globular head and 65C6 Fab complex. The head is coloured in green, the heavy chain in blue and light chain in yellow. (b) The globular head and 65C6 Fab complex is superimposed onto the A/Anhui/1/05 HA trimer. HA1 is coloured in pink and HA2 in cyan on one of three monomers. (c) Closer view of the 65C6 epitope residues shown as green stick. Key residues identified through the yeast surface mutant library are highlighted in red. (d–i) show the similar contents as that of a–c except for AVFluIgG03 and 100F4 Fab, respectively.

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