Figure 3: Ligand recognition by chromodomains.
From: Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction
(a) Close-up view of the backbone interactions of CD3 with A3CT IV. Hydrogen bonds are indicated by dashed lines. (b) Sequence alignment of chromodomain ligands. The 0 position binding to the cage is depicted in red. (c) Specific read-out of the 0 position in different chromodomains. Left: A3CT IV in CD3, middle: RRKRp in CD2, right: H3K9me3 in HP1. (d) Schematic representations of the respective chromodomain–ligand interactions.
