Figure 2: Body weight, lipid profiles, water consumption and food intake in SENP1-deficient mice. | Nature Communications

Figure 2: Body weight, lipid profiles, water consumption and food intake in SENP1-deficient mice.

From: SENP1-mediated NEMO deSUMOylation in adipocytes limits inflammatory responses and type-1 diabetes progression

Figure 2

(a) Body weight in Ctrl and SENP1-aP2KO mice was measured at the indicated ages (n=6 male in each group). (b) Body mass index (BMI) was calculated as body weight (g) divided by the square of the anal-nasal length (cm2) at the indicated ages. (c,d) Body weights in Ctrl, SENP1-adipoqKO and SENP1-PdgfRKO mice were measured at the indicated ages (male; n=8 for each group). (e,f) Mean blood lipoprotein levels in Ctrl and SENP1-aP2KO mice at the ages of 14 and 18 weeks (male; n=8 for each group). (g) Mean blood FFA levels in Ctrl and SENP1-aP2KO mice at indicated age (male; n=8 for each group). (h,i) Water consumption and mean daily food intake were measured in Ctrl and SENP1-aP2KO at indicated ages (male; n=8 for each group). The two-tailed Student’s paired t-test was used for the statistical analysis. All data are presented as means±s.e.m., n=8. *P<0.05; **P<0.01; Ctrl, control; NS, non-significance.

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