Figure 5: Reduced EC Icam-1 and Vcam-1 in M4K4 KD plaques.
From: Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis
(a,b) Control and M4K4 KD mice were fed WD for 16 weeks. Aortic arch sections were stained for Cd31 as an endothelial marker (green), Icam-1 (red, (a)), Vcam-1 (red, (b)) or DAPI. From left, CD31, Icam-1/Vcam-1, DAPI and merge. Scale bars, 100 μm. Arrowheads indicate Cd31/Icam-1 or Cd31/Vcam-1 colocalization. Images are representative of at least three control and three M4K4 KD animals. DAPI, 4,6-diamidino-2-phenylindole.
