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Low SHBG is a better indicator of metabolic syndrome than low total testosterone

Nature Clinical Practice Endocrinology & Metabolism volume 4, page 478 (2008)Cite this article

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Chubb SA et al. (2008) Lower sex hormone-binding globulin is more strongly associated with metabolic syndrome than lower total testosterone in older men: the Health in Men study. Eur J Endocrinol 158: 785–792

Previous studies suggested that decreased testosterone levels are associated with an increased risk of metabolic syndrome in aging men. Chubb and colleagues, therefore, examined the relative contributions of levels of total testosterone, free testosterone and SHBG to this increased risk of metabolic syndrome. They found that measurements of SHBG best identify those at risk of the metabolic syndrome.

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Low SHBG is a better indicator of metabolic syndrome than low total testosterone. Nat Rev Endocrinol 4, 478 (2008). https://doi.org/10.1038/ncpendmet0912

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