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Diminished Oleic Acid Absorption in Man by L-Phenylalanine Inhibition of an Intestinal Phosphohydrolase

Nature New Biology volume 231, pages 116–117 (1971)Cite this article

Abstract

EXPERIMENTS in our laboratory have shown that a change in the position and concentration of intestinal alkaline phosphatase (IAP) in the jejunal mucosa is induced by absorption of oleic acid. To determine whether alkaline phosphatase and fatty acid absorption are causally related, we investigated the effect of an inhibitor of IAP, L-phenylalanine, on the rate of absorption of oleic acid (C18) in man.

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Authors and Affiliations

  1. Departments of Medicine and Pathology, Tufts University School of Medicine, Boston, Massachusetts, 02111

    WILLEM G. LINSCHEER, J. R. MALAGELADA & WILLIAM H. FISHMAN

Authors
  1. WILLEM G. LINSCHEER
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  2. J. R. MALAGELADA
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  3. WILLIAM H. FISHMAN
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LINSCHEER, W., MALAGELADA, J. & FISHMAN, W. Diminished Oleic Acid Absorption in Man by L-Phenylalanine Inhibition of an Intestinal Phosphohydrolase. Nature New Biology 231, 116–117 (1971). https://doi.org/10.1038/newbio231116a0

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