Abstract
Synthesis of viral DNA seems to be necessary for the production of “late” SV40 mRNA. Inhibitors of DNA synthesis, however, seem to prevent the appearance of late mRNA only in cells transformed by SV40 and not in infected cells.
This is a preview of subscription content, access via your institution
Access options
Similar content being viewed by others
References
Aloni, Y., Winocour, E., and Sachs, L., J. Mol. Biol., 31, 415 (1968).
Oda, K., and Dulbecco, R., Proc. US Nat. Acad. Sci., 60, 525 (1968).
Sauer, G., and Kidwai, J. R., Proc. US Nat. Acad. Sci., 61, 1256 (1968).
Martin, M. A., and Axelrod, D., Proc. US Nat. Acad. Sci., 64, 1203 (1969).
Oda, K., and Joklik, W., J. Mol. Biol., 27, 395 (1917).
Butel, J. S., and Rapp, F., Virology, 27, 490 (1965).
Kit, S., Dubbs, D. R., Frearson, P. M., and Melnick, J. L., Virology, 29, 69 (1966).
Jensen, F. C., Girardi, A. J., Gilden, R. V., and Koprowski, H., Proc. US Nat. Acad. Sci., 52, 53 (1964).
Koprowski, H., Jensen, F. C., and Steplewski, Z., Proc. US Nat. Acad. Sci., 58, 127 (1967).
Levin, M. J., Oxman, M. N., Diamandopoulos, G. T., Levine, A. S., Henry, P. H., and Enders, J. F., Proc. US Nat. Acad. Sci., 62, 589 (1969).
Rapp, F., Butel, J. S., Feldman, L. A., Kitahara, T., and Melnick, J. L., J. Exp. Med., 121, 935 (1965).
Defendi, V., Carp, R. I., and Gilden, R. V., in Viruses Inducing Cancer, 269 (University of Utah Press, Salt Lake City).
Sabin, A. B., Proc. US Nat. Acad. Sci., 55, 1141 (1966).
Carp, R. I., Sauer, G., and Sokol, F., Virology, 37, 214 (1969).
Travers, A. A., and Burgess, R. R., Nature, 222, 537 (1969).
Burgess, R. R., Travers, A. A., Dunn, J. J., and Bautz, E. K. F., Nature, 221, 43 (1969).
Sauer, G., and Hahn, E. C., Z. Krebsforschung, 74, 40 (1970).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SAUER, G. Apparent Differences in Transcriptional Control in Cells productively Infected and Transformed by SV40. Nature New Biology 231, 135–138 (1971). https://doi.org/10.1038/newbio231135a0
Received:
Revised:
Issue date:
DOI: https://doi.org/10.1038/newbio231135a0
This article is cited by
-
Sensitive quantitation of unlabelled SV40 cRNA by competition hybridization with3H-labelledin vitro cRNA
Medical Microbiology and Immunology (1972)