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Aminoacylation of Bisulphite-modified Yeast Tyrosine Transfer RNA

Nature New Biology volume 232, pages 177–179 (1971)Cite this article

Abstract

AS part of a search for the chemical rules underlying the recognition of a tRNA by its aminoacyl-tRNA ligase1, we are examining the effect of C⇐U transitions on aminoacylation of tRNA. In this paper, we describe four well-characterized modifications of yeast tRNATyr induced by reaction with bisulphite ions at pH 5.8. Three of the observed changes proved to be C-⇐U transitions produced by the series of reactions shown in Fig. 1 (refs. 2–5).

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Author notes

  1. ŽELJKO KUĆAN and IRA KUĆAN: On leave from the Institute Rudjer Bošković, Zagreb.

Authors and Affiliations

  1. University Medical Center of New York, 550 First Avenue, New York, New York, 10016

    ŽELJKO KUĆAN, KENNETH A. FREUDE, IRA KUĆAN & ROBERT W. CHAMBERS

Authors
  1. ŽELJKO KUĆAN
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  2. KENNETH A. FREUDE
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  3. IRA KUĆAN
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  4. ROBERT W. CHAMBERS
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KUĆAN, Ž., FREUDE, K., KUĆAN, I. et al. Aminoacylation of Bisulphite-modified Yeast Tyrosine Transfer RNA. Nature New Biology 232, 177–179 (1971). https://doi.org/10.1038/newbio232177a0

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