Abstract
COLONY formation by irradiated surface-attached mammalian cells in culture requires that at least one of the progeny produced at the first post-irradiation division retains the capacity for unlimited division. Abortive colonies result when the irradiated parent cell has experienced sufficient damage to suppress eventual colony formation, but not to prevent the production of a small number of progeny. We now present data which indicate that, if given a suitable environment, progeny from cells “lethally” damaged by X-radiation (not capable of producing a macroscopic colony) can repair damage transferred (sectored) from the parent cell.
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References
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BELLI, J. Daughter Cell Repair by Mammalian Cells in Culture after Potentially Lethal Radiation Damage. Nature New Biology 233, 47–48 (1971). https://doi.org/10.1038/newbio233047a0
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DOI: https://doi.org/10.1038/newbio233047a0
