Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Cell-free Studies on the Regulation of the Arabinose Operon

Abstract

A DNA directed, cell-free system which synthesized L-ribulokinase coded by the L-arabinose operon ara OIBAD, has been developed. L-arabinose but not the araC gene product is required for the expression of this operon and, in addition, cyclic AMP and guanosine tetraphosphate are needed for optimal synthesis.

This is a preview of subscription content, access via your institution

Access options

Similar content being viewed by others

References

  1. Englesberg, E., Squires, C., and Meronk, jun., F., Proc. US Nat. Acad. Sci., 62, 1100 (1969).

    Article  CAS  Google Scholar 

  2. Zubay, G., Schwartz, D., and Beckwith, J., Proc. US Nat. Acad. Sci., 66, 104 (1970).

    Article  CAS  Google Scholar 

  3. Emmer, M., deCrombrugghe, B., Pastan, I., and Perlman, R., Proc. US Nat. Acad. Sci., 66, 480 (1970).

    Article  CAS  Google Scholar 

  4. Katz, L., and Englesberg, E., J. Bacterial., 71 (in the press).

  5. Riggs, A., Reiness, G., and Zubay, G., Proc. US Nat. Acad. Sci. (in the press).

  6. Chambers, D., Cheong, L., and Zubay, G., in The Lac Operon (edit. by Zipser, D., and Beckwith, J.) (Cold Spring Harbor Laboratory of Quantitative Biology, New York, 1970).

    Google Scholar 

  7. Englesberg, E., in Metabolic Pathways (edit. by Greenberg, D., and Vogel, H.) (in the press).

  8. deCrombrugghe, B., Chen, B., Gottesman, M., Pastan, I., Varmus, H. E., Emmer, M., and Perlman, R. L., Nature, 230, 37 (1971).

    CAS  Google Scholar 

  9. Lee, N., and Englesberg, E., Proc. US Nat. Acad. Sci., 50, 696 (1963).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

ZUBAY, G., GIELOW, L. & ENGLESBERG, E. Cell-free Studies on the Regulation of the Arabinose Operon. Nature New Biology 233, 164–165 (1971). https://doi.org/10.1038/newbio233164a0

Download citation

  • Received:

  • Revised:

  • Issue date:

  • DOI: https://doi.org/10.1038/newbio233164a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing