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Multiple Human T K Chromosomes in Human-Mouse Somatic Cell Hybrids

Abstract

Selection treatment can enrich a population of human-mouse hybrid cells for those cells containing multiple copies of the thymidine kinase chromosome.

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  1. Harris, H., Watkins, J. F., Campbell, G. L. M., Evans, E. P., and Ford, C. E., Nature, 207, 606 (1965).

    Article  CAS  Google Scholar 

  2. Kao, F. T., and Puck, T. T., Nature, 228, 329 (1970).

    Article  CAS  Google Scholar 

  3. Weiss, M. C., and Green, H., Proc. US Nat. Acad. Sci., 58, 1104 (1967).

    Article  CAS  Google Scholar 

  4. Migeon, B. R., and Miller, C. S., Science, 162, 1005 (1968).

    Article  CAS  Google Scholar 

  5. Matsuya, Y., Green, H., and Basilico, C., Nature, 220, 1199 (1968).

    Article  CAS  Google Scholar 

  6. Migeon, B. R., Smith, S. W., and Leddy, C. L., Biochem. Genetics, 3, 583 (1969).

    Article  CAS  Google Scholar 

  7. Hayflick, L., and Moorhead, P., Exp. Cell Res., 25, 585 (1961).

    Article  CAS  Google Scholar 

  8. Matsuya, Y., and Green, H., Science, 163, 697 (1969).

    Article  CAS  Google Scholar 

  9. Wang, R., Pollack, R., Kusano, T., and Green, H., J. Virol., 5, 677 (1970).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Davidson, R., and Ephrussi, B., Nature, 205, 1170 (1965).

    Article  Google Scholar 

  11. Littlefleld, J. W., Science, 145, 709 (1964).

    Article  Google Scholar 

  12. Miller, O. J., Allderdice, P. W., Miller, D. A., Breg, W. R., and Migeon, B. R., Science, 173, 244 (1971).

    Article  CAS  Google Scholar 

  13. Marin, G., and Littlefield, J. W., J. Virol., 2, 69 (1968).

    CAS  PubMed  PubMed Central  Google Scholar 

  14. Littlefleld, J. W., Biochim. Biophys. Acta, 114, 398 (1966).

    Article  Google Scholar 

  15. Shin, S., Khan, P. M., and Cook, P. R., Biochem. Genet., 5, 91 (1971).

    Article  CAS  Google Scholar 

  16. Pollack, R. E., Green, H., and Todaro, G. J., Proc. US Nat. Acad. Sci., 60, 126 (1968).

    Article  CAS  Google Scholar 

  17. Miller, O. J., Cook, P. R., Meera Khan, P., Shin, S., and Siniscalco, M., Proc. US Nat. Acad. Sci., 68, 116 (1971).

    Article  CAS  Google Scholar 

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GREEN, H., WANG, R., KEHINDE, O. et al. Multiple Human T K Chromosomes in Human-Mouse Somatic Cell Hybrids. Nature New Biology 234, 138–140 (1971). https://doi.org/10.1038/newbio234138a0

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