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End-to-End Association of X and Y Chromosomes in Mouse Meiosis

Nature New Biology volume 236, pages 29–30 (1972)Cite this article

Abstract

ACCORDING to the hypothesis of Crew and Koller1 and Koller and Darlington2, there are homologous segments in the X and Y chromosomes of the mouse and other mammals. The homologous regions in the mouse were believed to be localized in the extremely short arms proximal to the kinetochores. The end-to-end association at meiosis was thought to be the result of the formation of a chiasma between these homologous regions3. Electron microscopy revealed a short synaptonemal complex in mouse meiotic cells4. However, partial sex linkage has never been demonstrated in the mouse5 and other authors6–10 believe that the X and Y chromosomes associate only by connexion between the chromosome ends furthest from the centromeres.

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Authors and Affiliations

  1. Histologisch-Embryologisches Institut der Universität, Wien, Schwarzspanierstrasse 17

    W. SCHNEDL

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  1. W. SCHNEDL
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SCHNEDL, W. End-to-End Association of X and Y Chromosomes in Mouse Meiosis. Nature New Biology 236, 29–30 (1972). https://doi.org/10.1038/newbio236029a0

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  • DOI: https://doi.org/10.1038/newbio236029a0

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