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Depression of Humoral Antibody Formation in the Chicken by Thymectomy and Antilymphocyte Serum

Nature New Biology volume 236, pages 79–80 (1972)Cite this article

Abstract

STUDIES on the chicken1 established that transplantation immunity and humoral antibody formation were two independent systems of immune reactivity which were under the developmental control of two distinct primary lymphoid organs—the thymus and the bursa of Fabricius. Although a clear distinction of the two primary lymphoid organs has not been made in mammals, a division between thymus-dependent (T cells) and thymus independent (B cells) lymphocyte functions is now well documented2,3. In the mouse, T cells are involved in cell mediated immune responses, and are also necessary for the full expression of the humoral antibody response to many antigens.

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References

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Authors and Affiliations

  1. Laboratory of Immunogenetics, The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Parkville, Victoria

    BARRY T. ROUSE & NOEL L. WARNER

Authors
  1. BARRY T. ROUSE
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  2. NOEL L. WARNER
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ROUSE, B., WARNER, N. Depression of Humoral Antibody Formation in the Chicken by Thymectomy and Antilymphocyte Serum. Nature New Biology 236, 79–80 (1972). https://doi.org/10.1038/newbio236079a0

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