Abstract
IT is not known whether the “anabolic” action of the androgenic hormone testosterone1, especially on muscular growth and metabolism, can be explained by the presence and the possible metabolism and “receptors” of the hormone in muscles. There are indeed several categories of muscles which, when dependent on androgens, may or may not respond directly to testosterone. It is conceivable that the hormone affects certain muscles through an increased (sexual or general) activity by way of the central nervous system, or because of the release of another hormone, or secondarily through some change of general metabolism.
This is a preview of subscription content, access via your institution
Access options
References
Kochakian, C. D., Proc. Soc. Exp. Biol. Med., 32, 1064 (1935).
Wainmann, P., and Shipounoff, G. C., Endocrinology, 29, 975 (1941).
Baulieu, E.-E., Lasnitzki, I., and Robel, P., Nature, 219, 1155 (1968).
Anderson, K. M., and Liao, S., Nature, 219, 277 (1968).
Bruchovsky, N., and Wilson, J. D., J. Biol. Chem., 243, 2012 (1968).
Gloyna, R. E., and Wilson, J. D., J. Clin. Endocrinol., 29, 970 (1969).
Callow, R. K., and Deanesly, R., Biochem. J., 29, 1424 (1935).
Eisenberg, E., and Gordon, G. S., J. Pharmacol. Exp. Therap., 99, 38 (1950).
Hershberger, L. G., Shipley, E. G., and Meyer, R. K., Proc. Soc. Exp. Biol. Med., 83, 175 (1953).
Kochakian, C. D., Protein Anabolic Property of Androgens, Ala. J. Med. Sci., 1, 24 (1964).
Mainwaring, W. I. P., J. Endocrinol., 45, 333 (1969).
Baulieu, E.-E., and Jung, I., Biochem. Biophys. Res. Comm., 38, 599 (1970).
Jung, I., and Baulieu, E.-E., Biochimie., 53, 807 (1971).
Mercier-Bodard, C., Alfsen, A., and Baulieu, E.-E., Acta Endocrinol., supp. 147, 64, 204 (1970).
Baulieu, E.-E., and Robel, P., Some Aspects of the Aetiology and Biochemistry of Prostatic Cancer (edit. by Griffiths, K., and Pierrepoint, C. G.), 74 (Tenovus Workshop Publications, Cardiff, 1970).
Buresova, M., and Gutmann, E., J. Endocrinol., 50, 643 (1971).
Baulieu, E.-E., Alberga, A., Jung, I., Lebeau, M. C., Mercier-Bodard, C., Milgrom, E., Raynaud, J. P., Raynaud-Jammet, C., Rochefort, H., Truong, H., and Robel, P., Rec. Prog. Hormone Res., 27, 351 (1971).
Endocrine Bioassay Data, No. 1 (edit. by Hilgar, A. G., and Hummel, D.) (CCNSC., NIH., Bethesda, Maryland, 1964).
Giannopoulos, G., Biochem. Biophys. Res. Commun., 44, 943 (1971).
Raspé, G. (ed.), Advances in the Biosciences, 7 (Pergamon, Vieweg, 1971).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
JUNG, I., BAULIEU, EE. Testosterone Cytosol “Receptor” in the Rat Levator Ani Muscle. Nature New Biology 237, 24–26 (1972). https://doi.org/10.1038/newbio237024a0
Received:
Revised:
Issue date:
DOI: https://doi.org/10.1038/newbio237024a0
This article is cited by
-
The MRL +/+ mouse: a new model of tubular aggregates which are gender- and age-related
Acta Neuropathologica (1989)
-
Anabolic effect of testosterone on the levator ani muscle of the rat
Pflügers Archiv European Journal of Physiology (1977)