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Prostaglandins inhibit Intestinal Sodium Transport

Nature New Biology volume 238, pages 26–27 (1972)Cite this article

Abstract

PROSTAGLANDINS1 are synthesized in the gut2 but their role, if any, on regulation of intestinal function is unknown. Oral administration of prostaglandins shortens intestinal transit time3 and several prostaglandin-producing tumours are associated with diarrhoea4. Infusion of prostaglandins and theophylline into the superior mesenteric artery of dogs results in the loss of gut fluid from jejunal loops5.

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Author notes

  1. QAIS AL-AWQATI

    Present address: Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, 02114

Authors and Affiliations

  1. Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205

    QAIS AL-AWQATI & WILLIAM B. GREENOUGH III

Authors
  1. QAIS AL-AWQATI
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  2. WILLIAM B. GREENOUGH III
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AL-AWQATI, Q., GREENOUGH, W. Prostaglandins inhibit Intestinal Sodium Transport. Nature New Biology 238, 26–27 (1972). https://doi.org/10.1038/newbio238026a0

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  • DOI: https://doi.org/10.1038/newbio238026a0

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