Abstract
ADENOSINE 3′,5′-cyclic monophosphate (cyclic AMP) has been shown to restore contact inhibition of transformed cells1 and to enhance the aggregation of thyroid cells2. I have studied the effects of exogenous and endogenous cyclic AMP on the centrifugal migration of guinea-pig macrophages from capillary tubes onto a glass surface. This test system is widely used for the measurement of a soluble lymphocyte product known as the migration inhibitory factor (MIF)3,4.
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PICK, E. Cyclic AMP affects Macrophage Migration. Nature New Biology 238, 176–177 (1972). https://doi.org/10.1038/newbio238176a0
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DOI: https://doi.org/10.1038/newbio238176a0
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