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Lymphoid Depletion and Immunosuppression after Thymectomy in the Young Pig

Abstract

SURGICAL thymectomy early in immunological development has profound effects on the immune responses of rodents and chickens: cell-mediated immune responses are very markedly inhibited and the humoral responses to some antigens are also depressed. Thymectomy in other species has been less well studied, and has given less marked but definite depression of certain immunological functions1,2. A previous study of neonatal thymectomy in the pig failed to demonstrate any consequent physiological changes3.

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BINNS, R., McFARLIN, D. & SUGAR, J. Lymphoid Depletion and Immunosuppression after Thymectomy in the Young Pig. Nature New Biology 238, 181–183 (1972). https://doi.org/10.1038/newbio238181a0

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