Abstract
The various enzymatic and non-enzymatic mechanisms proposed for the degradation of haem to bile pigments are critically reviewed. The importance of accurate methods of determining isomeric status of bile pigments in relation to these mechanisms is emphasized.
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Gray, C. H., Nicholson, D. C., & Nicolaus, R. A., Nature, 181, 183 (1958).
Petryka, Z. J., Proc. Soc. Exp. Biol. Med., 123, 464 (1966).
Foulkes, E. C., Lemberg, R., & Purdom, P., Proc. Roy. Soc. Lond., B, 138, 386 (1951).
Colleran, E., & O'Carra, P., Biochem. J., 119, 905 (1970).
O'Carra, P., & Colleran, E., FEBS Lett., 5, 295 (1969).
Holden, H. F., Amt. J. Exp. Biol. Med. Sci., 23, 255 (1946). 25, 47 (1947).
Snyder, A., & Schmid, R., J. Lab. Clin. Med., 65, 817 (1965).
Nakajima, H., Takemura, T., Nakajima, O., & Yamaoka, K., J. Biol. Chem., 238, 3784 (1963).
Nakajima, O., in Bile Pigment Metabolism (edit. by Bouchier, I. A. D., and Billing, B. H.), 55 (Blackwell, Oxford and Edinburgh).
Gray, C. H., & Nakajima, O., Biochem. J., 104, 20 (1967).
Gray, C. H., Nicholson, D. C., & Petryka, Z. J., Nature, 194, 1047 (1962).
Tenhunen, R., Marver, H. S., & Schmid, R., J. Biol. Chem., 224, 6388 (1969).
Gray, C. H., & Nakajima, O., Biochem. J., 111, 23P (1969).
Wise, C. D., & Drabkin, D. C., Fed. Proc. Amer. Soc. Exp. Biol., 23, 223 (1964).
Wise, C. D., & Drabkin, D. C., Fed. Proc. Amer. Soc. Exp. Biol., 24, 222 (1965).
Colleran, E., & O'Carra, P., Biochem. J., 115, 13P (1969).
O'Carra, P., & Colleran, E., J. Chromatog., 50, 458 (1970).
Murphy, R. F., O hEocha, C., & O'Carra, P., Biochem. J., 104, 6C (1967).
Levin, E. Y., Biochim. Biophys. Acta, 136, 155 (1967).
Nicolaus, R. A., Rass. Med. Sper., 7 (Suppl. 2), 1 (1960).
Tipton, G., & Gray, C. H., J. Chromatog., 59, 29 (1971).
Rüdiger, W., Z. Physiol. Chem., 350, 1291 (1969).
Rüdiger, W., in Porphyrins and Related Compounds (edit. by Goodwin, T. W.), 121 (Academic Press, New York, 1969).
McDonagh, A. F., & Bonnett, R., Chem. Commun., 273 (1970).
Nichol, A. W., & Morell, D. B., Biochim. Biophys. Acta, 184, 173 (1969).
McDonagh, A. F., & Assisi, F., FEBS Lett., 18, 315 (1971).
Bonnett, R., & McDonagh, A. F., Chem. Commun., 238 (1970).
Stoll, M. S., & Gray, C. H., Biochem. J., 117, 271 (1970).
Kondo, T., Nicholson, D. C., Jackson, A. H., & Kenner, G. W., Biochem. J., 121, 601 (1971).
Tenhunen, R., Marver, H., Pimstone, N. R., Trager, W. F., Cooper, D. Y., & Schmid, R., Biochemistry (in the press).
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GRAY, C., NICHOLSON, D. & TIPTON, G. Degradation of Haem Compounds to Bile Pigments. Nature New Biology 239, 5–8 (1972). https://doi.org/10.1038/newbio239005a0
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DOI: https://doi.org/10.1038/newbio239005a0
