Abstract
THE radio-immunoassay (RIA) of neurophysin, using an antiserum directed against an antigenic fragment common to various neurophysins, has enabled us to show that this hypo-thalamo-neurohypophysial carrier of active hormones such as vasopressin or antidiuretic hormone (ADH) and oxytocin (Oxy) is released concomitantly with them in various animal species both in vitro1–2; and in vivo. It appeared therefore that RIA of neurophysin could be a useful tool to explore neurohypophysial activity directly.
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LEGROS, J., GRAU, J. Effect of Ethinyl-Oestradiol on Some Neurohypophysial Active Compounds in the Rat. Nature New Biology 241, 247–249 (1973). https://doi.org/10.1038/newbio241247a0
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DOI: https://doi.org/10.1038/newbio241247a0