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Is Gene Amplification RNA-directed?

Abstract

Gene amplification in oocytes has been thought to involve a “reverse transcriptase” like that found in the RNA tumour viruses. Neither the template RNA nor the hybrid intermediates required by this theory can be detected in amplifying ovaries.

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BIRD, A., ROGERS, E. & BIRNSTIEL, M. Is Gene Amplification RNA-directed?. Nature New Biology 242, 226–230 (1973). https://doi.org/10.1038/newbio242226a0

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