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Cyclic AMP-amplified Replication of RNA Tumour Virus-like Particles in Chinese Hamster Ovary Cells

Nature New Biology volume 244, pages 227–231 (1973)Cite this article

Abstract

Treatment of Chinese hamster ovary cells (CHO-K1) with dibutyryl cyclic AMP and testosterone increases the production of RNA tumour virus-like particles thirty-fold or more, and induces a large increase in agglutinability by concanavalin A.

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References

  1. Hsie, A. W., and Puck, T. T., proc. natn. Acad. Sci. U.S.A., 68, 358 (1971).

    Article  CAS  Google Scholar 

  2. Hsie, A. W., Jones, C., and Puck, T. T., Proc. natn. Acad. Sci. U.S.A., 68, 1648 (1971).

    Article  CAS  Google Scholar 

  3. Johnson, G. S., Friedman, R. M., and Pastan, I., Proc. natn. Acad. Sci. U.S.A., 68, 425 (1971).

    Article  CAS  Google Scholar 

  4. Sheppard, J. R., Proc. natn. Acad. Sci. U.S.A., 68, 1316 (1971).

    Article  CAS  Google Scholar 

  5. Sheppard, J. R., Nature new Biol., 236, 14 (1972).

    Article  CAS  Google Scholar 

  6. Johnson, G. S., and Pastan, I., J. natn. Cancer Inst., 48, 1377 (1972).

    CAS  Google Scholar 

  7. Burger, M. M., Proc. natn. Acad. Sci. U.S.A., 62, 994 (1969).

    Article  CAS  Google Scholar 

  8. Otten, J., Bader, J., Johnson, G. S., and Pastan, I., J. biol. Chem., 247, 1632 (1972).

    CAS  PubMed  Google Scholar 

  9. Albino, A. P., deHarven, E., and Kingsley Sanders, F., J. Virol., 10, 477 (1972).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Maia, J. C. C., Rougeon, F., and Chapeville, F., FEBS Lett., 18, 130 (1971).

    Article  CAS  Google Scholar 

  11. Penner, P. E., Cohen, L. H., and Loeb, L. A., Nature new Biol., 232, 58 (1971).

    Article  CAS  Google Scholar 

  12. Starvianopoulos, J. G., Karkas, J. D., and Chargaff, E., Proc. natn. Acad. Sci. U.S.A., 68, 2207 (1971).

    Article  Google Scholar 

  13. Fridlender, B., Fry, M., Bolden, A., and Weissbach, A., Proc. natn. Acad. Sci. U.S.A., 69, 452 (1972).

    Article  CAS  Google Scholar 

  14. Baltimore, D., and Smoler, D., Proc. natn. Acad. Sci. U.S.A., 68, 1507 (1971).

    Article  CAS  Google Scholar 

  15. McCaffrey, R., Smoler, D. F., and Baltimore, D., Proc. natn. Acad. Sci. U.S.A., 70, 521 (1973).

    Article  CAS  Google Scholar 

  16. Green, M., Rokutanda, M., Fujinaga, K., Ray, R. K., Rokutanda, H., and Gurgo, C., Proc. natn. Acad. Sci. U.S.A., 67, 385 (1970).

    Article  CAS  Google Scholar 

  17. Schlom, J., and Spiegelman, S., Science, N.Y., 174, 840 (1971).

    Article  CAS  Google Scholar 

  18. Salzberg, S., and Green, M., Nature new Biol., 240, 116 (1972).

    Article  CAS  Google Scholar 

  19. Todaro, G., Proc. natn. Acad. Sci. U.S.A., 69, 1009 (1972).

    Article  CAS  Google Scholar 

  20. Hong, J. S., Smith, G. R., and Ames, B. N., Proc. natn. Acad. Sci. U.S.A., 68, 2258 (1971).

    Article  CAS  Google Scholar 

  21. Smith, B. J., Defendi, V., and Wigglesworth, N. M., Virology, 51, 230 (1973).

    Article  CAS  Google Scholar 

  22. Langan, T. A., Science, N.Y., 162, 579 (1968).

    Article  CAS  Google Scholar 

  23. D'armiento, M., Johnson, G. S., and Pastan, I., Proc. natn. Acad. Sci. U.S.A., 69, 459 (1972).

    Article  CAS  Google Scholar 

  24. Forn, J., Tagliamonte, A., Tagliamonte, P., and Gessa, G. L., Nature new Biol., 237, 245 (1972).

    Article  CAS  Google Scholar 

  25. Blatti, S. P., Ingles, C. J., Lindell, T. J., Morris, P. W., Weaver, R. F., Weinberg, F., and Rotter, W. J., Cold Spring Harbor Symp. Quant. Biol., 35, 649 (1970).

    Article  CAS  Google Scholar 

  26. Inbar, M., and Sachs, L., Proc. natn. Acad. Sci. U.S.A., 63, 1418 (1969).

    Article  CAS  Google Scholar 

  27. Salzberg, S., and Raskas, H. J., Virology, 48, 631 (1972).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. St Louis University School of Medicine, Institute for Molecular Virology, 3681 Park Avenue, St Louis, Missouri, 63110

    CLAUDE TIHON & MAURICE GREEN

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  1. CLAUDE TIHON
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  2. MAURICE GREEN
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TIHON, C., GREEN, M. Cyclic AMP-amplified Replication of RNA Tumour Virus-like Particles in Chinese Hamster Ovary Cells. Nature New Biology 244, 227–231 (1973). https://doi.org/10.1038/newbio244227a0

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