Abstract
MANDEL1 has shown, using freeze fracture, that the intramembranous particles of many murine lymphocytes are found in well-defined, tightly packed aggregates. Experiments where athymic “nude” mice or mice depleted of T cells were used, resulted in a decrease in the total number of lymphocytes exhibiting this aggregation; it was therefore suggested that only T lymphocytes contained clustered particles.
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References
Mandel, T. E., Nature new Biol., 239, 112 (1972).
Claman, H. N., Chaperon, E. A., and Triplett, R. F., Proc. Soc. exp. Biol. Med., 122, 1167 (1966).
Mishell, R. I., and Dutton, R. W., J. exp. Med., 126, 423 (1967).
Branton, D., Proc. natn. Acad. Sci. U.S.A., 55, 1048 (1966).
McIntyre, J. A., and Pierce, C. W., J. Immun. (in the press).
Loor, F., Eur. J. Immun., 3, 112 (1973).
McIntyre, J. A., Gilula, N. B., and Karnovsky, M. J., J. Cell Biol, (in the press).
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MCINTYRE, J., KARNOVSKY, M. & GILULA, N. Intramembranous Particle Aggregation in Lymphoid Cells. Nature New Biology 245, 147–148 (1973). https://doi.org/10.1038/newbio245147a0
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DOI: https://doi.org/10.1038/newbio245147a0
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