Figure 4: Posterior probabilities for site classes under alternative models along the gene for each amino-acid site calculated by Bayes empirical Bayes analysis. | Nature Genetics

Figure 4: Posterior probabilities for site classes under alternative models along the gene for each amino-acid site calculated by Bayes empirical Bayes analysis.

From: The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits

Figure 4

Class 1 sites are under purifying selection (Ka/Ks ratio of ∼0), class 2 sites are under neutral selection (Ka/Ks ratio of ∼1), and class 3 sites are under positive selection in Xiphophorus species. (a) Insulin-like growth factor 2 (IGF2). Colored bars below the plot show known functional domains, and the arrow shows the proteolysis site (between residues 118 and 119). (b) ChoriogeninH minor. Top, comparison of egg-laying versus livebearing fish. Bottom, comparison of placental versus non-placental mammals. The same regions are under positive selection in fishes and mammals.

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