Supplementary Figure 5: Sequence alignment for human podocin and Pyrococcus horikoshii stomatin
From: Mutation-dependent recessive inheritance of NPHS2-associated steroid-resistant nephrotic syndrome
There is a 35% identity and 65% homology for the modeled region (podocin residues 161-332): colored boxes show identities. Arrows above the sequence indicate the domain structure. Cyan corresponds to the N-terminal cytosolic fragment, magenta to the intra-membrane fragment and green to the C-terminal cytosolic fragment of podocin.
