Supplementary Figure 8: Transcript levels of SLC30A8 variants.
From: Loss-of-function mutations in SLC30A8 protect against type 2 diabetes
nCounter analysis of SLC30A8 transcript levels in HeLa cells, following transient over-expression of C-terminal, V5-tagged ZnT8 variants and control ORFs. Data shown are mean, normalized mRNA counts ± s.e.m. of three independent plasmid transfections from two experiments. Non-specific binding is indicated by the red line. Gene expression detected by probes directed against the SLC30A8 sequence encoding the N terminus, the sequence encoding the V5 tag, and TUBB are shown.
