Supplementary Figure 5: Expression pattern of endogenous TM6SF2 in wild-type C57BL/6J mouse | Nature Genetics

Supplementary Figure 5: Expression pattern of endogenous TM6SF2 in wild-type C57BL/6J mouse

From: Systematic evaluation of coding variation identifies a candidate causal variant in TM6SF2 influencing total cholesterol and myocardial infarction risk

Supplementary Figure 5

This figure shows the tissue distribution pattern of TM6SF2 in C57BL/6J mouse. Endogenous Tm6sf2 was highly expressed in the liver at both mRNA and protein levels. (a) The mRNA level of Tm6sf2 was determined by Northern blotting. The ethidium bromide (EB) staining of 28S and 18S Ribosomal RNAs (rRNA) was used as a positive control. (b) The protein level of TM6SF2 in tissues was detected by Western blotting, and the fast green staining of blot served as an internal control. Tissues were collected from wild-type C57BL/6J mouse. SKM refers to skeletal muscle.

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