Supplementary Figure 5: Genome-wide LOH analysis on SCCOHT samples. | Nature Genetics

Supplementary Figure 5: Genome-wide LOH analysis on SCCOHT samples.

From: Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type

Supplementary Figure 5

Genome-wide LOH analysis was carried out for samples sequenced by whole-exome sequencing (Online Methods). Recurrent LOH is seen only on chromosome 19p, where SMARCA4 is located (shown in pink). The top three rows show tumor samples with no LOH on chromosome 19p. Rows 4 and 5 show the matched normal and tumor sample seen in Supplementary Figure 1, where row 4 is normal DNA and row 5 is matched tumor DNA with LOH on chromosome 19p. Rows 6−12 show samples with LOH on chromosome 19p, with the region of homozygosity represented in pink.

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