Supplementary Figure 2: Event graph and Circos plot of chromothripsis in DIPG29.
(a) The bidirected event graph for a chromothripsis event in DIPG29. Red edges represent the genomic interval of their respective nodes. Blue edges represent groups of discordant read pairs supporting the same breakpoint. Arc width is proportional to the maximal likely copy count. (b) A Circos plot of chromosomes 1 and 2 from MYCN group patient DIPG29. Only those clusters larger than 1,000 bp are shown between chr. 1 and chr. 2. The width of each arc is proportional to the log of its estimated copy count. The highest estimated copy count is 61.
